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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDX1
All Species:
20.3
Human Site:
T213
Identified Species:
40.61
UniProt:
P52945
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52945
NP_000200.1
283
30771
T213
D
K
K
R
G
G
G
T
A
V
G
G
G
G
V
Chimpanzee
Pan troglodytes
A2T756
283
30712
T213
D
K
K
R
G
G
G
T
A
V
G
G
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001096758
281
30575
T213
D
K
K
R
G
G
G
T
A
V
G
G
G
G
V
Dog
Lupus familis
XP_543155
532
56855
T462
D
K
K
R
S
C
G
T
A
P
G
G
V
A
D
Cat
Felis silvestris
Mouse
Mus musculus
P52946
284
30981
T214
D
K
K
R
S
S
G
T
P
S
G
G
G
G
G
Rat
Rattus norvegicus
P52947
283
30812
T213
D
K
K
R
S
S
G
T
T
S
G
G
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519548
259
28495
G210
E
E
D
K
K
K
G
G
A
G
P
G
G
A
P
Chicken
Gallus gallus
XP_001234636
231
26345
R170
N
K
Y
I
S
R
P
R
R
V
E
L
A
V
M
Frog
Xenopus laevis
P14837
271
31388
S214
D
K
K
R
G
R
G
S
D
P
E
Q
D
S
V
Zebra Danio
Brachydanio rerio
O42370
396
43083
L278
P
Q
Q
N
I
Y
G
L
A
A
Y
T
A
P
L
Tiger Blowfish
Takifugu rubipres
Q1KKS7
408
44369
L290
P
Q
Q
N
M
Y
G
L
A
A
Y
T
A
P
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999815
390
43430
Q282
A
K
R
K
P
L
K
Q
D
A
D
G
S
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.2
49.6
N.A.
87.6
88.6
N.A.
64.3
63.2
57.9
26.7
26.9
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
99.2
98.5
50
N.A.
89.4
90.1
N.A.
71
70.6
66.7
36.6
36.7
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
100
100
60
N.A.
66.6
66.6
N.A.
26.6
13.3
46.6
13.3
13.3
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
60
N.A.
66.6
66.6
N.A.
46.6
26.6
53.3
33.3
33.3
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
59
25
0
0
25
17
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
9
0
0
0
0
0
17
0
9
0
9
9
9
% D
% Glu:
9
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
34
25
84
9
0
9
50
67
50
42
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
75
59
17
9
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
17
0
0
0
9
0
0
17
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
9
0
9
0
9
17
9
0
0
17
9
% P
% Gln:
0
17
17
0
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
59
0
17
0
9
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
34
17
0
9
0
17
0
0
9
9
0
% S
% Thr:
0
0
0
0
0
0
0
50
9
0
0
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
34
0
0
9
9
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
17
0
0
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _